Trinucleotide Disorders
- polymorphic: many forms include variable number of repeats from person to person
- more repeats with each generation
Fragile X
- symptoms similar to down syndrome
Frederich's Ataxia
- brain, heart, pancreas depend on mitochondria
Huntington
Myotonic Dystrophy
- muscle disorder along with DMD, becker
- loss of myotonic dystrophy protein kinase
- CTG
- later than other muscular dystrophies
- triad: Cataracts, Toupee, Gonadal atrophy
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